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Senior Associate Scientist - Receptor Biology

Company: Amgen Inc.
Location: Thousand Oaks
Posted on: November 16, 2021

Job Description:

HOW MIGHT YOU DEFY IMAGINATION? You've earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you've worked hard to acquire and the passion you already have. At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world's leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role. Senior Associate Scientist - Receptor Biology Live What you will do Let's do this. Let's change the world. The Cardiometabolic Disorders Department at Amgen in Thousand Oaks is seeking a highly motivated Sr. Associate Scientist. In this vital role you will join a team of investigators in pursuit of innovative treatments for obesity and the related cardiometabolic disorders. The successful candidate is expected to: * Drive the advancement of drug discovery projects by performing in vitro laboratory experiments under minimal supervision and working closely with a group of committed scientists * With some supervision, plan, conduct or monitor experiments, record and organize data, analyze results, troubleshoot, generate robust and reliable data * Exhibit expertise in a wide range of molecular and cellular biology techniques, such as primary cell culture, stable cell line development, functional cell-based assay development, CRISPR/Cas-based genome editing, immunoassays (western blot, ELISA, flow cytometry, immunofluorescence staining, etc.), RT-qPCR, fluorescent microscopy, and other imaging methods as necessary * Operate and maintain standard lab equipment * Document experimental plans and procedures timely with great attention to detail. * Exhibit self-motivation and proactive attitude in designing and conducting experiments using ground breaking technologies * Present preclinical data internally and engage coworkers in scientific discussions * Contribute to internal/external reports, presentations, regulatory documents, invention disclosure submissions and/or patents * Understand when to seek input and when to make independent judgments Win What we expect of you We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a scientist with these qualifications. Basic Qualifications: Master's degree and 3 years experience in molecular biology, cell biology, or related field Or Bachelor's degree and 5 years of experience in molecular biology, cell biology, or related field Preferred qualifications: * Strong conceptual background in molecular biology, cell biology, or biochemistry * Experience studying membrane-juxtaposed signaling cascade down stream of GPCR, Receptor-tyrosine kinase (RTK) and other receptors. * Hands-on experience with mammalian cell culture technique including primary cell culture, transient and stable transfection * Experience performing molecular biology experiments, such as RNA, DNA extraction, qPCR, cloning, CRISPR/Cas9-based genome editing * Experience performing antibody-based experiments such as flow cytometry (3+ colors), ELISA, immunofluorescence imaging and western blot * Hand-on experience in handling samples in 96-well format * Critical thinking and attention to detail * Strong organizational, analytical and problem-solving skills * Interpersonal, verbal, and written communication skills. * Proficiency in GraphPad Prism, Microsoft Word, Excel, and PowerPoint * Strong desire to discover ground-breaking therapeutics for cardiometabolic diseases such as obesity and fatty liver disease. Thrive Some of the vast rewards of working here As we work to develop treatments that take care of others, so we work to care for our teammates' professional and personal growth and well-being. * Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey * A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act * Generous Total Rewards Plan-comprising health, finance and wealth, work/life balance, and career benefits-with compensation and benefits rated above 4 stars (out of 5) on Glassdoor Apply now for a career that defies imagination Objects in your future are closer than they appear. Join us. careers.amgen.com Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.

Keywords: Amgen Inc., Thousand Oaks , Senior Associate Scientist - Receptor Biology, Accounting, Auditing , Thousand Oaks, California

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