Senior Associate Scientist - Genome Editing and Cell Line Engineering

Company: Amgen Inc. (IR)
Location: Thousand Oaks
Posted on: May 24, 2023

Job Description:

Senior Associate Scientist - Genome Editing and Cell Line Engineering page is loaded Senior Associate Scientist - Genome Editing and Cell Line Engineering Apply locations US - California - Thousand Oaks time type Full time posted on Posted Yesterday job requisition id R-164755 Career CategoryScientificJob DescriptionHOW MIGHT YOU DEFY IMAGINATION?You've worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world's leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.Senior Associate Scientist - Genome Editing and Cell Line EngineeringLiveWhat you will doLet's do this. Let's change the world. In this vital role you will will be a part of Amgen's Induced Proximity Platform (IPP) organization. The IPP team is focused on developing novel drug modalities that use proximity biology to go after challenging drug targets in diverse therapeutic areas, such as Oncology, Cardiometabolic disorders and Inflammation. The Target Evaluation group in IPP is seeking a motivated Senior Associate Scientist to further develop our cell line engineering platform and enhance our cell-based screening capability. The successful candidate will work collaboratively with teams within IPP as well as with teams in chemistry and the different therapeutic areas.Specific responsibilities

• Design, optimize, and implement genome editing tools.
• Contribute to the development and streamlining of a cell line engineering pipeline
• Functionally characterize engineered cell lines and develop high throughput screening assays
• Interact with IPP team members and co-workers across different departments and research sites and communicate and present data in department and team meetings.
• Contribute results and participate in the writing of manuscripts for publication.WinWhat we expect of youWe are all different, yet we all use our unique contributions to serve patients. The unique professional we seek is a strong collaborator with these qualifications.Basic Qualifications:
  • Master's degree and 4 years of relevant scientific experience or
  • Bachelor's degree and 6years of relevant scientific experiencePreferred Qualifications:
    • An advanced degree with experience in cell line engineering and CRISPR based genome editing
    • A track record of scientific achievement, supported by publications and/or significant contributions to a drug discovery program
    • Experience with mammalian cell culture techniques and gene delivery methods
    • Experience with molecular biology techniques (cloning, plasmid design, DNA extraction, DNA amplification)
    • Knowledge and/or hands-on experience with biochemical techniques (protein extraction, western blot, immunoprecipitation)
    • Knowledge and/or hands-on experience with high throughput, plate-based assays
    • Knowledge and/or hands-on experience with flow cytometry, fluorescence imaging techniques
    • Excellent organizational, interpersonal and communication skills
    • Flexibility to work in teams to achieve changing project goals and meet timelines
    • Strong data analysis and independent critical thinking skillsThriveWhat you can expect of usAs we work to develop treatments that take care of others, we also work to care for our teammates' professional and personal growth and well-being.The annual base salary range for this opportunity in the U.S. is $103,045-125,031.In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
      • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
      • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
      • Stock-based long-term incentives
      • Award-winning time-off plans and bi-annual company-wide shutdowns
      • Flexible work models, including remote work arrangements, where possibleApply nowfor a career that defies imaginationObjects in your future are closer than they appear. Join us.careers.amgen.com.Salary Range103,045.00 USD - 125,031.00 USD Similar Jobs (2) IPP Target Evaluation and Targeted Protein Degradation locations US - California - Thousand Oaks time type Full time posted on Posted Yesterday Molecular and Cell Biologist locations US - California - Thousand Oaks time type Full time posted on Posted Yesterday About Us Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.For more information, visit www.amgen.com -and follow us on www.twitter.com/amgen

Keywords: Amgen Inc. (IR), Thousand Oaks , Senior Associate Scientist - Genome Editing and Cell Line Engineering, Engineering , Thousand Oaks, California