Executive Director, Security Architecture and Engineering

Company: Amgen
Location: Thousand Oaks
Posted on: December 1, 2025

Job Description:

At Amgen, if you feel like you are a part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. What you will do Lets do this. Lets change the world. In this vital role the Executive Director, Security Architecture and Engineering is responsible for setting the strategic vision and leading several of Amgens security and protection capabilities across core domains including network, cloud, data, software, endpoint, mobile and AI. This individual will be accountable for defining and executing a strategic security architecture and engineering roadmap, ensuring trust in Amgens digital backbone, and delivering a secure, resilient, and compliant foundation that enables Amgens continued growth and innovation at scale. This leader will direct a global team and will ensure high-performing day-to-day operations while driving transformative initiatives such as AI security/protection, Zero Trust Network deployment, and next-generation data and mobile security. The role requires deep technical expertise in cybersecurity engineering domains as well as relevant frameworks (NIST, ISO, CIS, HIPAA, GDPR, GxP) and the ability to collaborate effectively with stakeholders across functions, including AI & Data, and several other enterprise teams. The ideal candidate has experience delivering enterprise-scale security engineering programs, managing global teams, and fostering innovation in highly regulated environments, driving initiatives that protect and strengthen digital trust and resilience across Amgen. This role requires strategic vision, operational discipline, and ability to influence at the executive level. Roles & Responsibilities: Defining Strategy Establish and direct the enterprise Security Architecture and Engineering strategy and multi-year roadmap, ensuring alignment with Amgens digital trust vision and business priorities across all protection domains (network, cloud, data, endpoint, mobile, AI, and software). Designing Architecture Set the architectural vision and governance model for secure integration across enterprise technology platforms and digital initiatives, driving consistency, scalability, and resilience. Delivering Capabilities Lead the engineering, implementation, and operation of protection technologiesincluding Zero Trust and AI securityensuring delivery to strategic milestones. Ensuring Compliance Oversee adherence to global regulatory, audit, and framework requirements (NIST, ISO, HIPAA, GDPR, GxP, 21 CFR Part 11), embedding compliance into design principles. Managing Operations Direct global teams to deliver reliable, scalable, and high-performing security services underpinned by measurable SLAs and KPIs. Collaborating with Stakeholders Partner closely with CDT, Infrastructure, AI/Data, and enterprise business leaders to embed security and trust into Amgens digital ecosystem and innovation agenda. Allocating Resources Drive investment and resource prioritization across architecture and engineering programs to maximize business impact and risk reduction. Developing Talent Build, mentor, and retain a diverse global workforce of architects and engineers, cultivating next-generation leadership and deep domain expertise. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a leader with these qualifications. Basic Qualifications: Doctorate degree & 6 years of cybersecurity experience OR Masters degree & 10 years of cybersecurity experience OR Bachelors degree & 12 years of cybersecurity experience AND 6 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources Preferred Qualifications: Expertise in security architecture, engineering, and operations across cloud, data, network, endpoint, mobile, and AI domains Experience leading large, distributed teams as well as developing and retaining talent Collaboration and influence skills to partner across cyber, infrastructure, Data & AI, and business functions Ability to manage multi-million-dollar budgets and optimize spend Experience in biotech, pharmaceutical, or other highly regulated industries Professional certifications such as CISSP, CCSP, CISM Familiarity with Zero Trust maturity models and AI/ML security frameworks Strategic Thinking: Defines long-term architecture strategy and anticipates emerging threats Transparent Decision-Making: Balances risk, compliance, and business needs in security investment choices Adaptive Leadership: Leads global teams through complex change in fast-moving digital environments. Leadership and team management skills Transformation and change management experience Executive communication and stakeholder management Ability to manage multiple priorities in a high-pressure environment What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The annual base salary range for this opportunity in the U.S. is $272,936 to $324,955. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans and bi-annual company-wide shutdowns Flexible work models, including remote work arrangements, where possible As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship for this role is not guaranteed.

Keywords: Amgen, Thousand Oaks , Executive Director, Security Architecture and Engineering, IT / Software / Systems , Thousand Oaks, California