Principal Agentic AI Chatbot Engineer
Company: Amgen
Location: Thousand Oaks
Posted on: December 1, 2025
|
|
|
Job Description:
Join Amgens Mission of Serving Patients At Amgen, if you feel
like youre part of something bigger, its because you are. Our
shared missionto serve patients living with serious illnessesdrives
all that we do. Since 1980, weve helped pioneer the world of
biotech in our fight against the worlds toughest diseases. With our
focus on four therapeutic areas Oncology, Inflammation, General
Medicine, and Rare Disease we reach millions of patients each year.
As a member of the Amgen team, youll help make a lasting impact on
the lives of patients as we research, manufacture, and deliver
innovative medicines to help people live longer, fuller happier
lives. Our award-winning culture is collaborative, innovative, and
science based. If you have a passion for challenges and the
opportunities that lay within them, youll thrive as part of the
Amgen team. Join us and transform the lives of patients while
transforming your career. Principal Agentic AI Chatbot Engineer
What you will do Lets do this. Lets change the world. In this vital
role you will lead the design, development, and deployment of
enterprise-scale agents and conversational bots . You will own the
end-to-end architecturefrom orchestration and retrieval to safety,
observability, and CI/CDso our agents reliably solve real business
problems across R&D, Manufacturing, and Commercial. As a senior
IC player-coach, youll set technical standards, mentor teams, and
partner with Security, Compliance, DevOps, and Product to ship
secure, resilient, and cost-efficient solutions with measurable
impact. Roles & Responsibilities: Own the enterprise agent/bot
platform architecture (cloud/on-prem), API contracts, and
guardrails for multi-tenant use. Design and ship production agentic
systems: multi-agent planning, tool/function calling, workflow
orchestration, and structured outputs. Build high-containment bots
for web/mobile/Slack/Teams/IVR with streaming responses and
sub-second turn latency where required. Implement retrieval &
memory (RAG, vector stores, knowledge graphs, session memory) with
data contracts, lineage, and lifecycle governance. Establish bot
CI/CD: prompt & config versioning, replay/conversation tests,
feature flags, and automated rollbacks. Implement progressive
delivery (blue-green, canary) with health checks, feature flags,
and one-click rollback. Stand up observability : tracing, metrics,
and conversation analytics (containment, escalation, hallucination,
CSAT, latency, cost per turn) with alerts and runbooks. Integrate
securely with enterprise systems (e.g., SAP, Salesforce,
ServiceNow, MES/LIMS/ELN/QMS) via robust connectors and
least-privilege tool access. Embed safety, privacy, and compliance
(content filtering, red-teaming, audit trails, secrets mgmt)
aligned to GxP/21 CFR Part 11 and HIPAA/PII needs. Optimize
inference and cost (routing, caching, batching,
distillation/quantization) and drive GPU/accelerator/FinOps
strategy. Evaluate and document trade-offs for models (open vs.
proprietary), hosting options, and agent frameworks (e.g.,
LangChain, Semantic Kernel, Assistants APIs). Translate domain
needs (R&D, Manufacturing, Commercial) into prioritized
roadmaps; mentor teams and communicate technical trade-offs to
stakeholders. What we expect of you We are all different, yet we
all use our unique contributions to serve patients. The
professional we seek will have these qualifications. Basic
Qualifications: Doctorate degree and 2 years of Computer Science,
IT or related field experience Or Masters degree and 4 years of
Computer Science, IT or related field experience Or Bachelors
degree and 6 years of Computer Science, IT or related field
experience Or Associates degree and 10 years of Computer Science,
IT or related field experience Or High school diploma / GED and 12
years of Computer Science, IT or related field experience Preferred
Qualifications: 3-5 years in AI/ML and enterprise software.
Knowledge graphs or structured reasoning (SPARQL, RDF/OWL) and
tool-use planning with constraints. Safety tooling (jailbreak
detection, content moderation, PII redaction) and automated
red-team pipelines. Experience with privacy-preserving patterns
(data masking, synthetic data, federated or on-prem inference).
Domain familiarity in biopharma workflows (clinical operations,
quality, manufacturing/supply chain, field/commercial). FinOps at
scale: GPU fleet planning, utilization dashboards, commitment
management. Contributions to open source in LLM/agent ecosystems;
patents or publications in conversational AI. Exceptional
stakeholder management; can translate complex technical concepts
into concise, outcome-oriented narratives. Good-to-Have Skills:
Experience in Biotechnology or pharma industry is a big plus
Published thought-leadership or conference talks on enterprise
GenAI adoption. Masters degree in Computer Science and or Data
Science Familiarity with Agile methodologies and Scaled Agile
Framework (SAFe) for project delivery. Certifications on GenAI/ML
platforms (AWS AI, Azure AI Engineer, Google Cloud ML, etc.) are a
plus. Soft Skills: Excellent analytical and troubleshooting skills.
Strong verbal and written communication skills Ability to work
effectively with global, virtual teams High degree of initiative
and self-motivation. Ability to manage multiple priorities
successfully. Team-oriented, with a focus on achieving team goals.
Ability to learn quickly, be organized and detail oriented. Strong
presentation and public speaking skills. What you can expect of us
As we work to develop treatments that take care of others, we also
work to care for your professional and personal growth and
well-being. From our competitive benefits to our collaborative
culture, well support your journey every step of the way. The
expected annual salary range for this role in the U.S. (excluding
Puerto Rico) is posted. Actual salary will vary based on several
factors including but not limited to, relevant skills, experience,
and qualifications. In addition to the base salary, Amgen offers a
Total Rewards Plan, based on eligibility, comprising of health and
welfare plans for staff and eligible dependents, financial plans
with opportunities to save towards retirement or other goals,
work/life balance, and career development opportunities that may
include: A comprehensive employee benefits package, including a
Retirement and Savings Plan with generous company contributions,
group medical, dental and vision coverage, life and disability
insurance, and flexible spending accounts A discretionary annual
bonus program, or for field sales representatives, a sales-based
incentive plan Stock-based long-term incentives Award-winning
time-off plans Flexible work models, including remote and hybrid
work arrangements, where possible Apply now and make a lasting
impact with the Amgen team. careers.amgen.com In any materials you
submit, you may redact or remove age-identifying information such
as age, date of birth, or dates of school attendance or graduation.
You will not be penalized for redacting or removing this
information. Application deadline Amgen does not have an
application deadline for this position; we will continue accepting
applications until we receive a sufficient number or select a
candidate for the position. As an organization dedicated to
improving the quality of life for people around the world, Amgen
fosters an inclusive environment of diverse, ethical, committed and
highly accomplished people who respect each other and live the
Amgen values to continue advancing science to serve patients.
Together, we compete in the fight against serious disease. Amgen is
an Equal Opportunity employer and will consider all qualified
applicants for employment without regard to race, color, religion,
sex, sexual orientation, gender identity, national origin,
protected veteran status, disability status, or any other basis
protected by applicable law. We will ensure that individuals with
disabilities are provided reasonable accommodation to participate
in the job application or interview process, to perform essential
job functions, and to receive other benefits and privileges of
employment. Please contact us to request accommodation.
Keywords: Amgen, Thousand Oaks , Principal Agentic AI Chatbot Engineer, IT / Software / Systems , Thousand Oaks, California
