Director Execution Excellence

Company: Amgen
Location: Thousand Oaks
Posted on: January 20, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Director Execution Excellence What you will do Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Director Business Performance Project Management What you will do Lets do this. Lets change the world. In this vital role you will join the Results Delivery Office (RDO) that drives transformation and builds critical capabilities that enable Amgen to respond to rapid advancements in science and technology within a rapidly changing business environment. We are looking for a Director Business Performance Project Management to join our team of leaders and liaisons, working on these high-priority initiatives that drive value through changes to our operating model and through simplification of Amgens largest, cross-functional, end-to-end processes. The Director Business Performance Project Management will report into a member of the RDO leadership team and will be assigned to the development and execution of one or more transformation initiatives related to Amgens core functions, e.g., Operations, R&D, Commercial, Medical Affairs, and/or Corporate Functions. This role requires a bold, dedicated leader with the ability to set enterprise priorities, apply advanced project management rigor, influence senior executives directly, and ensure speed to impact across Amgens most critical initiatives Lead transformation programs or workstreams to deliver business solutions from problem-solving through implementation, incl: Conduct qualitative and quantitative analyses to elucidate opportunities. Define KPIs and outcome measures (e.g., cost, quality, NPS) to monitor process health and set continuous improvement targets. Facilitate alignment on case for change, vision, ambition targets and realization measures and boldly frame trade-offs with senior leaders to accelerate decisions. Problem solve, ideate solutions, build business cases; ensure operational plans are in place to realize value: governance, measurements, resources, continuous improvement. Embed closed feedback loops and outcome metrics in the plan to verify impact and inform iteration. Design and lead working sessions/workshops. Structure sessions to prioritize improvement opportunities and sequence implementation for maximum enterprise impact. Design, develop and deliver key deliverables and presentation materials that facilitate decision-making with senior leaders. Provide clear decision paths and project management transparency (risks, dependencies, timelines). Lead a team to support transformation programs and/or lead workstreams. Set direction, coach for modernized approaches, and hold teams accountable to outcome measures. Drive execution excellence on transformation programs by leading the development and management of the workstream roadmap, project schedule, and status reporting (either directly or by member of your team). Ensure consistent application of project management practices across workstreams and rapid issue resolution. Lead development and facilitation of phase-appropriate change management strategies, plans and execution activities. Link change activities to measurable adoption and business outcomes. Liaise and coordinate across transformation and business teams and manage escalation of issues as needed. Proactively surface risks and bold, insightful recommendations directly to senior executives when escalation is warranted. Partner with RDO capability leads to apply process mapping, realization metrics, workshop facilitation, and change management as relevant to workstream needs. Emphasize defining and tracking outcome measures and integrating data needs for technology builds (especially automation). Coach and provide experiences that enable career development for RDO talent supporting your program. Foster a culture of iteration, speed to decision, and modernized toolkits. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications. Basic Qualifications: Doctorate degree and 4 years of business performance experience Or Masters degree and 8 years of business performance experience Or Bachelors degree and 10 years of business performance experience In addition to meeting at least one of the above requirements, you must have at least 4 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above. Preferred Qualifications: Proven track record leading enterprise-wide, tech-enabled transformation initiatives with measurable outcomes. Experience defining and managing outcome measures and KPIs for large-scale change programs. Demonstrated ability to influence senior executives with bold, insightful recommendations. Experience prioritizing and sequencing cross-functional improvements to maximize enterprise impact. Familiarity with automation, data integration, and advanced business performance tools. Strong leadership presence with the ability to set direction and inspire cross-functional alignment. What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Keywords: Amgen, Thousand Oaks , Director Execution Excellence, IT / Software / Systems , Thousand Oaks, California