HOW MIGHT YOU DEFY IMAGINATION?
You've earned your degree. How will you use that achievement to
reach your goals? Do more with the knowledge you've worked hard to
acquire and the passion you already have. At Amgen, our shared
mission-to serve patients-drives all that we do. It is key to our
becoming one of the world's leading biotechnology companies,
reaching over 10 million patients worldwide. Become the
professional you are meant to be in this meaningful role.
What you will do
Let's do this! Let's change the world!
Amgen's Process Development organization is seeking a Scientist
(Lvl 5B) to join the Pre-Pivotal Drug Substance Technologies
organization and be responsible for developing innovative solutions
to drive our small molecule pipeline. The scientist will be
involved in the dynamic transition of new programs / molecular
targets from Discovery Chemistry, into the clinical development
space, and through Clinical Proof of Concept (Early Phase Chemical
Development). The scientist will be primarily involved in the use
of innovative process technologies to drive route selection
activities and the development of chemical processes to be utilized
in the manufacture of Drug Substance to help drive our growing and
dynamic Small Molecule Portfolio.
Develops technology to manufacture drug candidates in a
practical, efficient, and safe manner.
Champions innovative applications of technology [High Throughput
Experimentation, Biocatalysis, Flow chemistry, process analytical
technologies (PAT)] to solve challenging synthetic problems and
drive improvements in sustainability, process efficiency, safety,
and cost of goods.
Provides significant contributions to drug substance development
teams (e.g., product and process development teams, product quality
teams) by providing drug substance updates, documentation, data
interpretation, technical recommendations, etc.
Serves as a technical expert and keeps current in organic
chemistry and applications of process technology in pharmaceutical
development including literature and technology development.
Improves the technical or scientific capabilities of the
department and routinely answers questions on or resolves
Collaborates in cross-functional teams to develop Amgen's
Works cross-functionally to deliver regulatory documents and
supporting documentation in support of Amgen's regulatory
Delivers processes amenable to manufacturing operations and
carry out deliveries of drug substance in a cGMP manufacturing
Ability and desire to lead synthetic route development, drive
new technology development, and eventually program management.
Effectively participates on drug substance development teams as
a team member.
Works effectively in a multi-disciplinary team of chemists,
engineers and attribute scientists.
- Collaborates with other scientists and professionals outside
What we expect of you
We are all different, yet we all use our unique contributions to
serve patients. The vital attribute professional we seek will have
Doctorate degree or Doctorate degree by December 2021
Master's degree and 4 years of scientific experience
Bachelor's degree and 6 years of scientific experience
Doctorate degree in Organic Chemistry, Medicinal Chemistry or
Post-doctoral research experience
Track record of demonstrated scientific accomplishments in the
field of organic chemistry
Ability to champion new technologies
Experience in the pharmaceutical / biotech or related industry
that includes participation and contribution to scientific project
Familiarity with common industrial unit operations including
crystallization (batch and continuous mode), filtration and
Familiarity with the use of design of experiments (DoE) and
Process Analytical Technology (PAT) techniques
Familiarity with laboratory automation, data analysis and
visualization techniques and tools
Familiarity with Environmental Health and Safety expectations
for chemical laboratories
Familiarity with current Good Manufacturing Practices for
preparing drug substances and intermediates
Demonstrated ability to effectively work in a fast-paced team
Excellent interpersonal, presentation, written and verbal
- Knowledge of basic office and chemistry software including
Microsoft Word, Excel, PowerPoint, ChemDraw, and SciFinder
Some of the vast rewards of working here
As we work to develop treatments that take care of others, so we
work to care for our teammates' professional and personal growth
Full support and career-development resources to expand your
skills, enhance your expertise, and maximize your potential along
your career journey
A diverse and inclusive community of belonging, where teammates
are empowered to bring ideas to the table and act
- Generous Total Rewards Plan-comprising health, finance and
wealth, work/life balance, and career benefits-with compensation
and benefits rated above 4 stars (out of 5) on Glassdoor
Apply now for a career that defies imagination
Objects in your future are closer than they appear. Join us.
Equal Opportunity Statement
Amgen is an Equal Opportunity employer and will consider you
without regard to your race, color, religion, sex, sexual
orientation, gender identity, national origin, protected veteran
status, or disability status.
We will ensure that individuals with disabilities are provided a
reasonable accommodation to participate in the job application or
interview process, to perform essential job functions, and to
receive other benefits and privileges of employment. Please contact
us to request an accommodation.
If you're seeking a career where you can truly make a difference
in the lives of others, a career where you can work at the absolute
forefront of biotechnology with the top minds in the field, you'll
find it at Amgen.
Amgen, a biotechnology pioneer, discovers, develops and delivers
innovative human therapeutics. Our medicines have helped millions
of patients in the fight against cancer, kidney disease, rheumatoid
arthritis and other serious illnesses.
As an organization dedicated to improving the quality of life
for people around the world, Amgen fosters an inclusive environment
of diverse, ethical, committed and highly accomplished people who
respect each other but compete intensely to win. Together, we live
the Amgen values as we continue advancing science to serve
Amgen is an Equal Opportunity employer and will consider all
qualified applicants for employment without regard to race, color,
religion, sex, sexual orientation, gender identity, national
origin, protected veteran status, or disability status.