Scientist, Research and Development

Company: Staffing Future Inc.
Location: Thousand Oaks
Posted on: May 14, 2023

Job Description:

Scientist, Research and Development
Thousand Oaks, California

Scientist, Research and Development
Thousand Oaks, CA
Direct-Hire, Full-Benefits
Mon-Fri 8 AM - 5 PM
Pay: 100-150K DOE
Job Summary:
The Scientist will join a cross-functional research team whose goal is to design and develop next-generation targeted delivery systems comprising various types of RNA payloads. This is a direct-hire, permanent position located in Thousand Oaks, CA with a schedule of Mon-Fri 8 AM - 5 PM.
Essential Duties:
--- Conducting scientific research for the development of novel nanoparticle therapeutics for hematologic and solid tumors
--- Independently planning, executing, and analyzing experiments to generate therapeutic candidates and advance them to the clinic
--- Thinking critically and creatively to generate ideas and executing those ideas to positively impact project goals
--- Serving as technical area expert with notable depth and breadth, maintaining a high level of expertise through familiarity with relevant scientific and technical literature
--- Collaborating with Biology colleagues for in vitro and in vivo characterization of therapeutics
--- Collaborating with colleagues in Chemistry and Manufacturing & Process Development to develop economical and scalable processes, and participating in technology transfer to
external Contract Development and Manufacturing Organizations (CDMOs)
--- Analyzing results, preparing technical presentations and reports, and presenting to cross functional teams and senior management
Qualifications:
--- Ph.D. in Chemistry or related field with 0-5 years additional relevant post-doctoral and/or industry experience
--- B.S. or M.S. degree with extensive industry experience
--- Expertise in organic polymer chemistry with an emphasis on synthetic methodology, total synthesis, and/or process chemistry
--- Strong synthetic skills and a solid knowledge of modern polymer synthesis techniques, with preference for those with hands-on experience with synthesis, purification, and characterization, as well as air-free techniques
--- Working knowledge of analytical techniques for characterization of compounds (e.g., GPC, NMR, HPLC)
--- Working knowledge of various polymerization strategies (e.g., polycondensation, RAFT, ROMP)
--- Working knowledge of non-viral, targeted nucleic acid delivery systems, with an emphasis on polymeric nanoparticles and mRNA payloads and analytical techniques for their characterization (e.g., particle size, zeta potential, encapsulation efficiency, dilution stability, RNA purity/integrity)
--- Preference for those with experience developing therapeutic candidates in the biopharmaceutical industry and familiarity with aspects of drug development, including formulation sciences, ADME, toxicology and regulatory requirements
--- Strong communication skills (both technical and non-technical, verbal and written), good problem-solving abilities, and an ability to work effectively and inclusively in a dynamic environment
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Keywords: Staffing Future Inc., Thousand Oaks , Scientist, Research and Development, Other , Thousand Oaks, California